1-[4-(三氟甲基)苯基]乙醇合成路线 （共 66 条）
反应条件
HCOONa; [Cp*RhCl2]2; (1R,2R)-N-(p-toluenesulfonyl)-1,2-diphenylethylenediamine in water T=40°C; 4 h; Reactivity; Time; optical yield given as percent eeenantioselective reaction;
参考文献
Chemistry - A European Journal, , vol. 14, # 7 p. 2209 - 2222
反应条件
3,3,3-trichloro-1,1,1-trifluoroacetone; toluene-4-sulfonic acid; hydroquinone in benzene 8 h; Heating;
参考文献
Abdel-Baky, Samy; Moussa, Adel
Synthetic Communications, 1988 , vol. 18, # 15 p. 1795 - 1800
反应条件
4,4'-diaminostilbene-2,2'-disulfonic acid in dichloromethane T=0 - 20°C;
参考文献
Kim, Kyu-Young; Bong, Chan Kim; Hee, Bong Lee; Shin, Hyunik
Journal of Organic Chemistry, 2008 , vol. 73, # 20 p. 8106 - 8108
反应条件
[IrH(1,5-cyclooctadiene)Cl(HCN(i-Pr)CHCN(C2H4PPh2))]PF6; potassium hydroxide in toluene T=110°C; 2 h; Inert atmosphere;
参考文献
Gong, Xue; Zhang, Hong; Li, Xingwei
Tetrahedron Letters, 2011 , vol. 52, # 43 p. 5596 - 5600
反应条件
1: 60 percent / P2O5 / benzene / 4 h / Heating 2: Br2 / diethyl ether / 2 h / -10 °C 3: 50 percent / KOH / H2O; diethyl ether / 180 - 220 °C View Scheme
参考文献
Journal of Chemical Research, Miniprint, , # 9 p. 3216 - 3245
反应条件
[(2-(benzoimidazol-2-yl)-6-(3,5-dimethylpyrazol-1-yl)pyridine)RuCl2(PPh3)]; potassium tert-butylate; acetone in methanol T=56°C; Oppenauer Oxidation; P=750.075 Torr; 0.5 h; Inert atmosphere; Catalytic behavior;
参考文献
Wang, Qingfu; Du, Wangming; Liu, Tingting; Chai, Huining; Yu, Zhengkun
Tetrahedron Letters, 2014 , vol. 55, # 9 p. 1585 - 1588
反应条件
palladium diacetate; oxygen; (-)-sparteine in 1,2-dichloro-ethane T=60°C; Title compound not separated from byproducts.;
参考文献
Sun, Wei; Wu, Xiaomei; Xia, Chungu
Helvetica Chimica Acta, 2007 , vol. 90, # 3 p. 623 - 626
反应条件
(S,S)-(-)-[N,N(1)-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminoat(2-)]manganese(III) chloride; [bis(acetoxy)iodo]benzene; potassium bromide in dichloromethane; water T=23°C; 0.5 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Brown, M. Kevin; Blewett, Megan M.; Colombe, James R.; Corey
Journal of the American Chemical Society, 2010 , vol. 132, # 32 p. 11165 - 11170
反应条件
C50H42ClN2O3Ru in chloroform T=25°C; Molecular sieveResolution of racemate; Kinetics; enantioselective reaction;
参考文献
Mizoguchi, Hirotaka; Uchida, Tatsuya; Katsuki, Tsutomu
Angewandte Chemie - International Edition, 2014 , vol. 53, # 12 p. 3178 - 3182
Angew. Chem., 2014 , vol. 126, # 12 p. 3242 - 3246,5
反应条件
1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 24 h / 25 °C 2: iodine / neat (no solvent) / 2 h / 85 °C View Scheme
参考文献
Jereb, Marjan; Vrazic, Dejan
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 12 p. 1978 - 1999
