1: 1.) sodium cyanoborohydride, 2.) bromocresol green, conc. HCl / 1.) THF, EtOH, 2.) THF, EtOH, 20 min 2: 2.775 g / C2H5ONa / ethanol / Heating 3: 91 percent / CH2Cl2 / 1 h / Ambient temperature 4: 95 percent / NaOH 5: 1.) Et3N, t-BuCOCl, 2.) n-BuLi 6: 4 N aq. HCl / dioxane 7: iPr2NEt / acetonitrile 8: 78 percent / aq. LiOH, 30percent aq. H2O2 / tetrahydrofuran / 0.5 h View Scheme