Z-TRP-GLY-OH合成路线 (共 10 条)
反应条件
sodium carbonate in 1,4-dioxane; water 24 h; Ambient temperature;
参考文献
Bespalova, Zhanna D.; Pekelis, Boris L.; Deigin, Vladislav I.; Yarova, Elena P.; Saks, Tatyana P.; et al.
Collection of Czechoslovak Chemical Communications, 1990 , vol. 55, # 10 p. 2537 - 2554
反应条件
triethylamine in water; acetonitrile
参考文献
Tetrahedron, , vol. 65, # 25 p. 4923 - 4929
反应条件
pyridine; sodium hydroxide 0.5 h;
参考文献
Bodanszky; Tolle; Seto; Sawyer
Journal of medicinal chemistry, 1980 , vol. 23, # 11 p. 1259 - 1261
反应条件
1: dicyclohexylcarbodiimide; dioxane 2: aqueous methanol. NaOH View Scheme
参考文献
Smith
Journal of Biological Chemistry, 1948 , vol. 175, p. 39,46
参考文献
Hofmann et al.
Journal of the American Chemical Society, 1958 , vol. 80, p. 1486,1488
反应条件
1: aqueous NaOH 2: PCl5; diethyl ether 3: ethyl acetate; aqueous NaOH View Scheme
参考文献
Smith
Journal of Biological Chemistry, 1948 , vol. 175, p. 39,46
反应条件
1: aqueous NaOH 2: PCl5; diethyl ether 3: ethyl acetate; aqueous NaOH View Scheme
参考文献
Smith
Journal of Biological Chemistry, 1948 , vol. 175, p. 39,46
反应条件
sodium hydroxide; ethyl acetate
参考文献
Smith
Journal of Biological Chemistry, 1948 , vol. 175, p. 39,46
反应条件
methanol; palladium; acetic acid Hydrogenation;
参考文献
Sidorova, M. V.; Kudryavtseva, E. V.; Molokoedov, A. S.; Ovchinnikov, M. V.; Bespalova, Zh. D.
Russian Journal of Bioorganic Chemistry, 1995 , vol. 21, # 9 p. 582 - 589
Bioorganicheskaya Khimiya, 1995 , vol. 21, # 9 p. 675 - 685
反应条件
1: N-methylmorpholine / tetrahydrofuran / 0.08 h / -15 °C
2: NH3 / tetrahydrofuran / 0.5 h / -15 °C
3: H2 / 10percent Pd/C / aq. ethanol / 3 h
View Scheme
参考文献
Bodanszky; Tolle; Seto; Sawyer
Journal of medicinal chemistry, 1980 , vol. 23, # 11 p. 1259 - 1261