二乙基[[3,4-(亚甲二氧基)苯胺基]亚甲基]丙二酸酯合成路线 （共 3 条）
反应条件
in benzene 3.5 h; Reflux;
参考文献
GENZYME CORPORATION; TEICHER, Beverly A.; SCHMID, Steven M.
Patent: WO2012/15875 A1, 2012 ;
Location in patent: Page/Page column 44-45 ;
反应条件
1: in methyloxirane T=120°C; 2 h; 2: With ammonium hydroxide in water pH=8;
参考文献
GENZYME CORPORATION; TEICHER, Beverly A.; SCHMID, Steven M.
Patent: WO2012/15875 A1, 2012 ;
Location in patent: Page/Page column 45 ;
反应条件
1: PPE / 2 h / 120 °C
2: NaOH / ethanol; H2O / 48 h / Ambient temperature
3: 52 percent / various solvent(s) / 1.5 h / Heating
4: 63 percent / phosphoryl chloride / 5 h / Heating
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参考文献
GENZYME CORPORATION; TEICHER, Beverly A.; SCHMID, Steven M.
Patent: WO2012/15875 A1, 2012 ;
