(-)-1,4-O-二苯基-L-苏醇合成路线 (共 11 条)
反应条件
in methanol 7 h; Heating;
参考文献
Dehmlow, Eckehard V.; Sauerbier, Christiane
Liebigs Annalen der Chemie, 1989 , p. 181 - 186
反应条件
anhydrous iron chloride; water in acetic acid T=20°C; 3 h;
参考文献
Tzschucke, C. Christoph; Pradidphol, Narathip; Dieguez-Vazquez, Alejandro; Kongkathip, Boonsong; Kongkathip, Ngampong; Ley, Steven V.
Synlett, 2008 , # 9 p. 1293 - 1296
反应条件
acetic acid in dichloromethane T=40°C;
参考文献
Mamidi, Narsimha; Gorai, Sukhamoy; Mukherjee, Rakesh; Manna, Debasis
Molecular BioSystems, 2012 , vol. 8, # 4 p. 1275 - 1285
反应条件
sulfuric acid in acetonitrile T=70°C; 4 h;
参考文献
Kanger, T. P.; Kabat, M.; Vikha, E.; Lopp, M. I.; Lille, Yu. E.
Journal of Organic Chemistry USSR (English Translation), 1990 , vol. 26, # 8 p. 1481 - 1484
Zhurnal Organicheskoi Khimii, 1990 , vol. 26, # 8 p. 1711 - 1714
反应条件
sulfuric acid in acetonitrile T=70°C; 4 h;
参考文献
Kanger, T. P.; Kabat, M.; Vikha, E.; Lopp, M. I.; Lille, Yu. E.
Journal of Organic Chemistry USSR (English Translation), 1990 , vol. 26, # 8 p. 1481 - 1484
Zhurnal Organicheskoi Khimii, 1990 , vol. 26, # 8 p. 1711 - 1714
反应条件
1: 100 percent / NaH; PTC / tetrahydrofuran 2: 99 percent / Dowex 50 WX4/H+ / ethanol View Scheme
参考文献
European Journal of Organic Chemistry, , # 9 p. 2033 - 2043
反应条件
1: N-bromoacetamide / acetone; H2O / Ambient temperature 2: 0.5 N H2SO4 / acetonitrile / 4 h / 70 °C View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 26, # 8 p. 1481 - 1484
Zhurnal Organicheskoi Khimii, , vol. 26, # 8 p. 1711 - 1714
反应条件
1: 60 percent / NaOH, tetrapropylammonium bromide / tetrahydrofuran / 24 h / Heating 2: 90 percent / HCl / acetone / 24 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 2 p. 321 - 327
参考文献
Journal of Medicinal Chemistry, , vol. 10, p. 927 - 932
反应条件
1: N-butylamine; copper dichloride / methanol / 1.5 h / 20 °C 2: potassium carbonate / acetone / 14 h / 20 °C / Inert atmosphere 3: sodium methylate / tetrahydrofuran; methanol / 24 h / Reflux View Scheme
参考文献
Journal of Organic Chemistry, , vol. 76, # 23 p. 9711 - 9719