1: With ammonium acetate; acetic acid in toluene 20 h; Heating; 2: With sulfur in ethanol T=65°C; 2 h; Further stages.;

暂无反应条件数据

1.1: pyridine / 2 h / 45 °C 2.1: 50.4 g / NaOMe / methanol / 6 h / 20 °C 3.1: 90 percent / KI; K2CO3 / dimethylformamide / 4 h / 20 °C 4.1: NBS; AIBN / chlorobenzene / 1.5 h / 90 °C 5.1: 33.0 g / i-Pr2NEt / dimethylformamide / 2 h / 20 °C 6.1: 87 percent / HCl; HCO2H / 10 percent Pd/C/water / diethyl ether / 3.5 h / 20 °C / atmospheric pressure 7.1: Et3N / CH2Cl2 / 24 h / 20 °C 7.2: 71 percent / Et3N / CH2Cl2 / 3 h / 20 °C View Scheme