2,4-二氯喹唑啉-7-甲酸甲酯合成路线 （共 3 条）
反应条件
1: With phosphorus pentachloride; trichlorophosphate Heating / reflux; 2: With sodium hydrogencarbonate in dichloromethane; water T=20°C; 1 h;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2007/125405 A2, 2007 ;
Location in patent: Page/Page column 20; 48-49; 54 ;
WO 2007/125405 A2
反应条件
1: 3 h / 200 °C 2: trichlorophosphate; N,N-dimethyl-aniline / 2 h / 120 °C View Scheme
反应条件
hydrogen; N-ethyl-N,N-diisopropylamine; palladium in ethyl acetate T=20°C; 1 h;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2007/125405 A2, 2007 ;
Location in patent: Page/Page column 20; 47; 54 ;
WO 2007/125405 A2
