4,4,5,5-四甲基-2-(1-苯基乙基)-1,3,2-二噁硼烷合成路线 （共 44 条）
反应条件
SPB; water in tetrahydrofuran T=22°C;
参考文献
Noh, Dongwan; Chea, Heesung; Ju, Junghwan; Yun, Jaesook
Angewandte Chemie, International Edition, 2009 , vol. 48, # 33 p. 6062 - 6064
Angewandte Chemie, 2009 , vol. 121, # 33 p. 6178 - 6180
反应条件
1: dichloromethane With n-butyllithium in tetrahydrofuran T=-100°C; Metallation; 0.166667 h; 2: 4,4,5,5-tetramethyl-2-(1-phenylethyl)-1,3,2-dioxaborolane With zinc(II) chloride in tetrahydrofuran; diethyl ether T=-100 - 20°C; Substitution; 3: With sodium chlorite in tetrahydrofuran; diethyl ether Oxidation; 48 h; Title compound not separated from byproducts;
参考文献
Chen, Austin C.; Ren, Li; Crudden, Cathleen M.
Chemical Communications, 1999 , # 7 p. 611 - 612
反应条件
phosphite dehydrogenase; recombinant phenylacetone monooxygenase from Thermobifida fusca; NADPH in dimethyl sulfoxide T=30°C; pH=7.5; 5 h; Tris/HCl bufferEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Brondani, Patricia B.; Dudek, Hanna; Reis, Joel S.; Fraaije, Marco W.; Andrade, Leandro H.
Tetrahedron Asymmetry, 2012 , vol. 23, # 9 p. 703 - 708
反应条件
phosphite dehydrogenase; recombinant phenylacetone monooxygenase from Thermobifida fusca; NADPH in dimethyl sulfoxide T=30°C; pH=9; 3 h; Tris/HCl bufferEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Brondani, Patricia B.; Dudek, Hanna; Reis, Joel S.; Fraaije, Marco W.; Andrade, Leandro H.
Tetrahedron Asymmetry, 2012 , vol. 23, # 9 p. 703 - 708
反应条件
SPB; water in tetrahydrofuran T=22°C;
参考文献
Noh, Dongwan; Chea, Heesung; Ju, Junghwan; Yun, Jaesook
Angewandte Chemie, International Edition, 2009 , vol. 48, # 33 p. 6062 - 6064
Angewandte Chemie, 2009 , vol. 121, # 33 p. 6178 - 6180
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=-78 - 20°C; Substitution; Homologation; 2: With sodium hydroxide; dihydrogen peroxide in methanol; diethyl ether T=20°C; Oxidation;
参考文献
Ren, Li; Crudden, Cathleen M.
Chemical Communications (Cambridge, United Kingdom), 2000 , # 8 p. 721 - 722
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=-78 - 20°C; Substitution; Homologation; 2: With sodium hydroxide; dihydrogen peroxide in methanol; diethyl ether T=20°C; Oxidation;
参考文献
Ren, Li; Crudden, Cathleen M.
Chemical Communications (Cambridge, United Kingdom), 2000 , # 8 p. 721 - 722
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=-78 - 20°C; Substitution; Homologation; 2: With sodium hydroxide; dihydrogen peroxide in methanol; diethyl ether T=20°C; Oxidation;
参考文献
Ren, Li; Crudden, Cathleen M.
Chemical Communications (Cambridge, United Kingdom), 2000 , # 8 p. 721 - 722
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=-78 - 20°C; Substitution; Homologation; 2: With sodium hydroxide; dihydrogen peroxide in methanol; diethyl ether T=20°C; Oxidation;
参考文献
Ren, Li; Crudden, Cathleen M.
Chemical Communications (Cambridge, United Kingdom), 2000 , # 8 p. 721 - 722
反应条件
1: in tetrahydrofuran; hexane T=-78 - 20°C; Substitution; Homologation; 2: With sodium hydroxide; dihydrogen peroxide in methanol; diethyl ether T=20°C; Oxidation;
参考文献
Ren, Li; Crudden, Cathleen M.
Chemical Communications (Cambridge, United Kingdom), 2000 , # 8 p. 721 - 722
