甲基2-羟基-3-甲基丁酸酯合成路线 （共 9 条）
反应条件
sulfuric acid Heating; Yield given;
参考文献
Nitsch, Dominik; Huber, Stefan M.; Poethig, Alexander; Narayanan, Arjun; Olah, George A.; Prakash, G. K. Surya; Bach, Thorsten
Journal of the American Chemical Society, 2014 , vol. 136, # 7 p. 2851 - 2857
反应条件
hydrogen; chiral Ru complex T=20°C; P=25857.4 Torr; 100 h; Title compound not separated from byproducts;
参考文献
Qiu, Liqin; Kwong, Fuk Yee; Wu, Jing; Lam, Wai Har; Chan, Shusun; Yu, Wing-Yiu; Li, Yue-Ming; Guo, Rongwei; Zhou, Zhongyuan; Chan, Albert S. C.
Journal of the American Chemical Society, 2006 , vol. 128, # 17 p. 5955 - 5965
反应条件
in diethyl ether T=24°C;
参考文献
Coleman, Robert S.
Journal of Organic Chemistry, 1993 , vol. 58, # 16 p. 4452 - 4461
反应条件
1: 4N H2SO4 / 24 h / Heating View Scheme
参考文献
Kelly, T. Ross; Arvanitis, Argyrios
Tetrahedron Letters, 1984 , vol. 25, # 1 p. 39 - 42
反应条件
1: conc. aq. HCl / 3 h / Heating 2: H2SO4 / Heating View Scheme
参考文献
Sundholm, Oskari; Kanerva, Liisa T.
ACH - Models in Chemistry, 1998 , vol. 135, # 4 p. 625 - 640
反应条件
1: sulfuric acid; sodium nitrite / 25 h / 0 - 20 °C / |Inert atmosphere; |Schlenk technique 2: acetyl chloride / 4 h / |Inert atmosphere; |Schlenk technique; |Reflux View Scheme
参考文献
Nitsch, Dominik; Huber, Stefan M.; Poethig, Alexander; Narayanan, Arjun; Olah, George A.; Prakash, G. K. Surya; Bach, Thorsten
Journal of the American Chemical Society, 2014 , vol. 136, # 7 p. 2851 - 2857
参考文献
Kelly, T. Ross; Arvanitis, Argyrios
Tetrahedron Letters, 1984 , vol. 25, # 1 p. 39 - 42
反应条件
1: Et3N, 4-N,N-dimethylaminopyridine / various solvent(s) / 6 h / 60 °C 2: 50 percent / potassium fluoride / formamide / 4 h / 95 °C / 12 Torr 3: 90 percent / formic acid View Scheme
参考文献
Fritz-Langhals, Elke; Schuetz, Gabi
Tetrahedron Letters, 1993 , vol. 34, # 2 p. 293 - 296
反应条件
1: 73 percent / imidazole
2: DIBAL-H / toluene / -78 °C
3: TBAF / tetrahydrofuran
View Scheme
参考文献
Humphrey, Andrew J.; Turner, Nicholas J.; McCague, Raymond; Taylor, Stephen J. C.
Journal of the Chemical Society, Chemical Communications, 1995 , # 24 p. 2475 - 2476
