2-[(2-硝基苯基)亚甲基]丙二酸二乙基酯合成路线 （共 15 条）
反应条件
hydrogen; nickel in ethanol
T=20°C; 12 h;
参考文献
Stover, James S.; Shi, Jin; Jin, Wei; Vogt, Peter K.; Boger, Dale L.
Journal of the American Chemical Society, 2009 , vol. 131, p. 3342 - 3348
反应条件
1: 48.5 g / H2 / Raney Ni / ethanol
2: 10.7 g / 96percent H2SO4, 70percent HNO3 / 1 h / 0 °C
3: 94 percent / 1.) 1 N NaOH; 2.) 1 N HCl / 1.25 h / Heating
View Scheme
参考文献
Hutt, Marland P.; MacKellar, Forrest A.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 349 - 352
反应条件
1: 48.5 g / H2 / Raney Ni / ethanol
2: 10.7 g / 96percent H2SO4, 70percent HNO3 / 1 h / 0 °C
3: 94 percent / 1.) 1 N NaOH; 2.) 1 N HCl / 1.25 h / Heating
4: 18.3 g / H2 / Raney Ni / dimethylformamide
View Scheme
参考文献
Hutt, Marland P.; MacKellar, Forrest A.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 349 - 352
反应条件
1: 48.5 g / H2 / Raney Ni / ethanol
2: 10.7 g / 96percent H2SO4, 70percent HNO3 / 1 h / 0 °C
3: 1.14 g / POCl3 / 2.75 h / Heating
View Scheme
参考文献
Hutt, Marland P.; MacKellar, Forrest A.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 349 - 352
反应条件
sodium cyanoborohydride in ethanol
参考文献
Hutchins,R.O. et al.
Journal of Organic Chemistry, 1976 , vol. 41, # 20 p. 3328 - 3329
