6-叔-丁基二甲基硅烷基-4’-羟基雷洛昔芬合成路线 (共 3 条)
反应条件
4-(N,N-dimethlyamino)pyridine in tetrahydrofuran; N,N-dimethyl-formamide
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 7 p. 887 - 892
反应条件
4-(N,N-dimethlyamino)pyridine 1.) THF, DMF, RT, 1 h, 2.) THF, DMF, RT, 72 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 2 p. 146 - 167
反应条件
boron trifluoride diethyl etherate in dichloromethane
参考文献
Dodge, Jeffrey A.; Lugar, Charles W.; Cho, Stephen; Osborne, John J.; Phillips, David L.; Glasebrook, Andrew L.; Frolik, Charles A.
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 8 p. 993 - 996