4-氟-5-(4-甲基哌嗪-1-基)苯-1,2-二胺合成路线 （共 4 条）
反应条件
hydrazine in ethanol T=30°C; Reflux;
参考文献
Mamedov, Vakhid A.; Zhukova, Nataliya A.; Balandina, Alsu A.; Kharlamov, Sergey V.; Beschastnova, Tat'Yana N.; Rizvanov, Il'Dar Kh.; Latypov, Shamil K.
Tetrahedron, 2012 , vol. 68, # 36 p. 7363 - 7373
反应条件
1: 95 percent 2: 75 percent / NH2NH2 / 10 percent Pd/C / ethanol View Scheme
参考文献
Konstantinova, Irina D.; Selezneva, Olga M.; Fateev, Ilja V.; Balashova, Tamara A.; Kotovskaya, Svetlana K.; Baskakova, Zoya M.; Charushin, Valery N.; Baranovsky, Alexander V.; Miroshnikov, Anatoly I.; Balzarini, Jan; Mikhailopulo, Igor A.
Synthesis (Germany), 2013 , vol. 45, # 2 art. no. SS-2012-T0784-OP, p. 272 - 280
反应条件
1: 95 percent 2: 75 percent / NH2NH2 / 10 percent Pd/C / ethanol View Scheme
参考文献
Kus, Canan; Goker, Hakan; Altanlar, Nurten
Archiv der Pharmazie, 2001 , vol. 334, # 11 p. 361 - 365
反应条件
1: 95 percent / dimethylsulfoxide / 140 - 145 °C 2: 82 percent / aq. HCl; SnCl2 / 2 h / 20 °C View Scheme
参考文献
Kus, Canan; Goker, Hakan; Altanlar, Nurten
Archiv der Pharmazie, 2001 , vol. 334, # 11 p. 361 - 365
