1,4-dihydro-1-propylpyridine-3-carboxamide; anhydrous magnesium perchlorate in acetonitrile Ambient temperature;

4 A molecular sieve; hydrogen; triethylamine; palladium in ethanol T=20°C; 44 h;

hydrogenchloride; [NH2Me2]+[{RuCl[(S)-SunPhos]}2(μ-Cl3)]; hydrogen in ethanol; water T=70°C; P=10501.1 Torr; 12 h; optical yield given as percent eeenantioselective reaction;

hydrogenchloride; [NH2Me2]+[{RuCl[(S)-SunPhos]}2(μ-Cl3)]; hydrogen in ethanol; water T=30°C; P=10501.1 Torr; 12 h; optical yield given as percent eeenantioselective reaction;