1: 95 percent / n-BuLi / tetrahydrofuran; hexane / a) 0 deg C, 75 min, b) RT, overnight 2: 84 percent / LiAlH4 / tetrahydrofuran / 6 h / Heating 3: 1.) n-BuLi, 2.) n-BuLi View Scheme

1: 95 percent / n-BuLi / tetrahydrofuran; hexane / a) 0 deg C, 75 min, b) RT, overnight 2: 88 percent / Br2 / acetic acid / 6 h / Ambient temperature View Scheme

1: 95 percent / n-BuLi / tetrahydrofuran; hexane / a) 0 deg C, 75 min, b) RT, overnight 2: 92 percent / 2,4-bis(4-methoxyphenyl)-1,3-dithia-2,4-diphosphetane-2,4-disulfide / toluene / 2 h / Heating View Scheme

n-butyllithium in tetrahydrofuran; hexane a) 0 deg C, 75 min, b) RT, overnight;

<b>Multi-step reaction with 2 steps<br /> </b>1: 70 percent / Et₃N, DMAP / CH₂Cl₂ / Ambient temperature<br />2: 60 percent / Et₃N, DMAP / CH₂Cl₂ / Heating<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 70 percent / Et₃N, DMAP / CH₂Cl₂ / Ambient temperature<br />2: 60 percent / Et₃N, DMAP / CH₂Cl₂ / Heating<br /> <br /> &nbsp;