(4R)-3-{(3S)-3-[3-(二苄基氨基)苯基]戊酰}-4-苯基-1,3-恶唑烷-2-酮合成路线 （共 8 条）
反应条件
1: 95 percent / n-BuLi / tetrahydrofuran / -78 °C 2: CuBr, DMS / tetrahydrofuran / 1 h / 0 °C 3: 1.) H3O+, 2.) Na2CO3 / 2.) H2O, CH2Cl2 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 119, # 15 p. 3627 - 3628
反应条件
1: 95 percent / n-BuLi / tetrahydrofuran / -78 °C 2: CuBr, DMS / tetrahydrofuran / 1 h / 0 °C 3: 1.) H3O+, 2.) Na2CO3 / 2.) H2O, CH2Cl2 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 119, # 15 p. 3627 - 3628
反应条件
1: CuBr, DMS / tetrahydrofuran / 1 h / 0 °C 2: 1.) H3O+, 2.) Na2CO3 / 2.) H2O, CH2Cl2 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 119, # 15 p. 3627 - 3628
反应条件
oxonium; sodium carbonate 2.) H2O, CH2Cl2; Yield given. Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 119, # 15 p. 3627 - 3628
反应条件
3: 67 percent / t-BuOK / tetrahydrofuran / 0 °C 4: H2 / Pd/C / methanol; ethyl acetate 5: 81 percent / pyridine / CH2Cl2 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 119, # 15 p. 3627 - 3628
反应条件
Yield given. Multistep reaction;
参考文献
Judge; Phillips; Morris; Lovasz; Romines; Luke; Tulinsky; Tustin; Chrusciel; Dolak; Mizsak; Watt; Vander Velde; Strohbach; Gammill
Journal of the American Chemical Society, 1997 , vol. 119, # 15 p. 3627 - 3628
反应条件
3: 67 percent / t-BuOK / tetrahydrofuran / 0 °C View Scheme
参考文献
Judge; Phillips; Morris; Lovasz; Romines; Luke; Tulinsky; Tustin; Chrusciel; Dolak; Mizsak; Watt; Vander Velde; Strohbach; Gammill
Journal of the American Chemical Society, 1997 , vol. 119, # 15 p. 3627 - 3628
参考文献
Judge; Phillips; Morris; Lovasz; Romines; Luke; Tulinsky; Tustin; Chrusciel; Dolak; Mizsak; Watt; Vander Velde; Strohbach; Gammill
Journal of the American Chemical Society, 1997 , vol. 119, # 15 p. 3627 - 3628
