2,3-二氢-2-甲基苯并呋喃合成路线 （共 55 条）
反应条件
bromine in tetrachloromethane T=20°C; Yield given;
参考文献
Ciba Geigy Corporation
Patent: US4560771 A1, 1985 ;
Title/Abstract Full Text Show Details
Ciba-Geigy Corporation
Patent: US4603211 A1, 1986 ;
反应条件
aluminium trichloride in dichloromethane T=20°C; 0.5 h;
参考文献
Daukshas, V. K.; Gaidyalis, P. G.; Pyatrauskas, O. Yu.; Udrenaite, E. B.
Pharmaceutical Chemistry Journal, 1994 , vol. 28, # 4 p. 246 - 248
Khimiko-Farmatsevticheskii Zhurnal, 1994 , vol. 28, # 4 p. 29 - 30
反应条件
1.1: n-butyllithium; N,N,N',N'-tetramethylethylenediamine / hexane / 1 h / 20 °C 1.2: 67 percent / -78 °C 2.1: SOCl2 / benzene / 3 h / Heating View Scheme
参考文献
Al-bojuk, Nader R.; El-Abadelah, Mustafa M.; Sabri, Salim S.; Michel, Alain; Voelter, Wolfgang; M.-Moessmer, Caecilia; Al-Abed, Yousef
Heterocycles, 2001 , vol. 55, # 9 p. 1789 - 1803
反应条件
1: 2-methyl-2,3-dihydrobenzofuran With n-butyllithium; N,N,N',N,-tetramethylethylenediamine in hexane T=20°C; 1 h; 2: carbon dioxide T=-78°C;
参考文献
Al-bojuk, Nader R.; El-Abadelah, Mustafa M.; Sabri, Salim S.; Michel, Alain; Voelter, Wolfgang; M.-Moessmer, Caecilia; Al-Abed, Yousef
Heterocycles, 2001 , vol. 55, # 9 p. 1789 - 1803
反应条件
aluminium trichloride in dichloromethane
T=20°C; 1 h;
参考文献
Daukshas, V. K.; Gaidyalis, P. G.; Pyatrauskas, O. Yu.; Udrenaite, E. B.; Gasperavichene, G. A.; Raguotene, N. V.
Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 5 p. 341 - 345
Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 5 p. 569 - 573
