(R)-2-二甲基氨基-1-苯基乙胺合成路线 （共 4 条）
反应条件
trifluoroacetic acid in dichloromethane 1.5 h; Ambient temperature;
参考文献
Giardina, Giuseppe A. M.; Raveglia, Luca F.; Grugni, Mario; Sarau, Henry M.; Farina, Carlo; Medhurst, Andrew D.; Graziani, Davide; Schmidt, Dulcie B.; Rigolio, Roberto; Luttmann, Mark; Cavagnera, Stefano; Foley, James J.; Vecchietti, Vittorio; Hay, Douglas W. P.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 6 p. 1053 - 1065
反应条件
1: 7.1 g / CH2Cl2 / 2 h / Ambient temperature 2: 73 percent / TEA / CH2Cl2 / 1.5 h / 0 °C 3: 3.5 g / ethanol / 2 h / 80 °C 4: 67 percent / TFA / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
Giardina, Giuseppe A. M.; Raveglia, Luca F.; Grugni, Mario; Sarau, Henry M.; Farina, Carlo; Medhurst, Andrew D.; Graziani, Davide; Schmidt, Dulcie B.; Rigolio, Roberto; Luttmann, Mark; Cavagnera, Stefano; Foley, James J.; Vecchietti, Vittorio; Hay, Douglas W. P.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 6 p. 1053 - 1065
反应条件
1: 3.5 g / ethanol / 2 h / 80 °C 2: 67 percent / TFA / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
Giardina, Giuseppe A. M.; Raveglia, Luca F.; Grugni, Mario; Sarau, Henry M.; Farina, Carlo; Medhurst, Andrew D.; Graziani, Davide; Schmidt, Dulcie B.; Rigolio, Roberto; Luttmann, Mark; Cavagnera, Stefano; Foley, James J.; Vecchietti, Vittorio; Hay, Douglas W. P.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 6 p. 1053 - 1065
反应条件
1: 73 percent / TEA / CH2Cl2 / 1.5 h / 0 °C 2: 3.5 g / ethanol / 2 h / 80 °C 3: 67 percent / TFA / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
Giardina, Giuseppe A. M.; Raveglia, Luca F.; Grugni, Mario; Sarau, Henry M.; Farina, Carlo; Medhurst, Andrew D.; Graziani, Davide; Schmidt, Dulcie B.; Rigolio, Roberto; Luttmann, Mark; Cavagnera, Stefano; Foley, James J.; Vecchietti, Vittorio; Hay, Douglas W. P.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 6 p. 1053 - 1065
