5-甲氧基-2-(三氟甲基)-1H-吲哚合成路线 （共 4 条）
反应条件
sec.-butyllithium in tetrahydrofuran T=-40°C; 2 h;
参考文献
EP1154774 B1, ;
Page/Page column 65 ;
反应条件
n-butyllithium in ethyl acetate
参考文献
American Cyanamid Company
Patent: US5502071 A1, 1996 ;
反应条件
trifluoroacetic acid in dichloromethane 24 h;
参考文献
WO2010/30727 A1, ;
Page/Page column 101 ;
WO 2010/030727 A1
反应条件
1: 92 percent / triphenyl phosphine; Et3N / CCl4 / 3 h / Heating 2: 88 percent / N-bromosuccinimide; benzoyl peroxide / CCl4 / Heating 3: 75 percent / magnesium / tetrahydrofuran / 2 h / 0 °C View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 128, # 10 p. 1143 - 1152
