1: 28 percent / lithium 2,2,6,6-tetramethylpiperidide / tetrahydrofuran / 3 h / -78 °C 2: 1.) lithium 2,2,6,6-tetramethylpiperidide, 2.) water / 1.) THF, -78 deg C, 2 h, 2.) THF, 25 deg C View Scheme

1: 28 percent / lithium 2,2,6,6-tetramethylpiperidide / tetrahydrofuran / 3 h / -78 °C 2: lithium 2,2,6,6-tetramethylpiperidide, lithium n-butoxide / tetrahydrofuran / 2 h / -78 °C View Scheme

2,2,6,6-tetramethylpiperidinyl-lithium in tetrahydrofuran T=-78°C; 3 h;