4-羟基-2-丁基氨基甲酸苄酯合成路线 （共 4 条）
反应条件
sodium hydrogencarbonate in tetrahydrofuran
参考文献
Jaervinen, Aki J.; Cerrada-Gimenez, Marc; Grigorenko, Nikolay A.; Khomutov, Alex R.; Vepsaelaeinen, Jouko J.; Sinervirta, Riitta M.; Keinaenen, Tuomo A.; Alhonen, Leena I.; Jaenne, Juhani E.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 1 p. 399 - 406
反应条件
diisobutylaluminium hydride in tetrahydrofuran; toluene 1.) -78 deg C, 1 h, 2.) -78 deg C to 0 deg C; 0 deg C, 1 h;
参考文献
Evans, P. Andrew; Holmes, Andrew B.; McGeary, Ross P.; Nadin, Alan; Russell, Keith; O'Hanlon, Peter J.; Pearson, Neil D.
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 2 p. 123 - 138
反应条件
1: 93 percent / SOCl2 / 1.) 0 deg C to r.t., 2.) r.t., 16 h 2: 90 percent / DIBAL-H / tetrahydrofuran; toluene / 1.) -78 deg C, 1 h, 2.) -78 deg C to 0 deg C; 0 deg C, 1 h View Scheme
参考文献
Sumi, Kengo; Inoue, Yoshihiro; Nishio, Masahiro; Naito, Yasuhito; Hosoya, Takamitsu; Suzuki, Masaaki; Hidaka, Hiroyoshi
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 3 p. 831 - 834
反应条件
1: 97 percent / aq. NaOH / tetrahydrofuran / 16 h / Ambient temperature 2: 93 percent / SOCl2 / 1.) 0 deg C to r.t., 2.) r.t., 16 h 3: 90 percent / DIBAL-H / tetrahydrofuran; toluene / 1.) -78 deg C, 1 h, 2.) -78 deg C to 0 deg C; 0 deg C, 1 h View Scheme
参考文献
Sumi, Kengo; Inoue, Yoshihiro; Nishio, Masahiro; Naito, Yasuhito; Hosoya, Takamitsu; Suzuki, Masaaki; Hidaka, Hiroyoshi
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 3 p. 831 - 834
