(R)-2-氨基-2-(4-氟苯基)乙醇合成路线 （共 3 条）
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=0 - 20°C; 17 h; 2: With sodium hydroxide in tetrahydrofuran; water 0.166667 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2005/49033 A1, 2005 ;
Location in patent: Page/Page column 114 ;
WO 2005/049033 A1
反应条件
sodium tetrahydroborate in ethanol; water T=0°C; RefluxInert atmosphere;
参考文献
Slattery, Catherine N.; O'Keeffe, Sarah; Maguire, Anita R.
Tetrahedron Asymmetry, 2013 , vol. 24, # 20 p. 1265 - 1275
参考文献
Pfizer Inc
Patent: US5952369 A1, 1999 ;
