1-苯基-1,2-二氢异喹啉-3(4H)-酮合成路线 （共 17 条）
反应条件
1: sodium tetrahydroborate; iodine / tetrahydrofuran / 16 h / |Inert atmosphere; |Reflux 2: methanol / 20 °C View Scheme
参考文献
Ghislieri, Diego; Green, Anthony P.; Pontini, Marta; Willies, Simon C.; Rowles, Ian; Frank, Annika; Grogan, Gideon; Turner, Nicholas J.
Journal of the American Chemical Society, 2013 , vol. 135, # 29 p. 10863 - 10869
反应条件
1.1: sodium tetrahydroborate; iodine / tetrahydrofuran / 16 h / |Inert atmosphere; |Reflux 2.1: hydrogenchloride; borane-ammonia complex / aq. phosphate buffer / 37 °C / pH 7.8 3.1: triethylamine / tetrahydrofuran / 2 h / 0 - 25 °C / |Inert atmosphere 4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / |Inert atmosphere 4.2: 4 h / 110 °C / |Inert atmosphere View Scheme
参考文献
Ghislieri, Diego; Green, Anthony P.; Pontini, Marta; Willies, Simon C.; Rowles, Ian; Frank, Annika; Grogan, Gideon; Turner, Nicholas J.
Journal of the American Chemical Society, 2013 , vol. 135, # 29 p. 10863 - 10869
反应条件
aluminium trichloride in 1,2-dichloro-benzene T=25°C; 240 h;
参考文献
Koltunov, Konstantin Yu.; Prakash, G. K. Surya; Rasul, Golam; Olah, George A.
Journal of Organic Chemistry, 2002 , vol. 67, # 25 p. 8943 - 8951
反应条件
1: sodium tetrahydroborate; iodine / tetrahydrofuran / 16 h / |Inert atmosphere; |Reflux 2: hydrogenchloride; borane-ammonia complex / aq. phosphate buffer / 37 °C / pH 7.8 View Scheme
参考文献
Ghislieri, Diego; Green, Anthony P.; Pontini, Marta; Willies, Simon C.; Rowles, Ian; Frank, Annika; Grogan, Gideon; Turner, Nicholas J.
Journal of the American Chemical Society, 2013 , vol. 135, # 29 p. 10863 - 10869
反应条件
1: 76 percent / PCl5 / 2 h / 115 - 120 °C 2: 97 percent / H2, NH3 / 10percent Pd/C / ethyl acetate; methanol / 2.5 h / 750.06 Torr / Ambient temperature View Scheme
参考文献
Renger, B.; Konz, E.; Rueger, W.
Synthesis, 1988 , # 9 p. 683 - 685
反应条件
1: sodium tetrahydroborate; iodine / tetrahydrofuran / 16 h / |Inert atmosphere; |Reflux 2: hydrogenchloride; borane-ammonia complex / aq. phosphate buffer / 37 °C / pH 7.8 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 135, # 29 p. 10863 - 10869
反应条件
sodium tetrahydroborate; iodine in tetrahydrofuran 16 h; Inert atmosphereReflux;
参考文献
Ghislieri, Diego; Green, Anthony P.; Pontini, Marta; Willies, Simon C.; Rowles, Ian; Frank, Annika; Grogan, Gideon; Turner, Nicholas J.
Journal of the American Chemical Society, 2013 , vol. 135, # 29 p. 10863 - 10869
反应条件
1: 62 percent / AlCl3 / 1,2-dichloro-benzene / 240 h / 25 °C 2: 67 percent / AlCl3 / cyclohexane / 3 h / 90 °C View Scheme
参考文献
Koltunov, Konstantin Yu.; Prakash, G. K. Surya; Rasul, Golam; Olah, George A.
Journal of Organic Chemistry, 2002 , vol. 67, # 25 p. 8943 - 8951
反应条件
sodium hydroxide; Aliquatreg; 336 in benzene
3 h; Ambient temperature;
参考文献
Hazai, Laszlo; Deak, Gyula; Szoelloesy, Aron; Toth, Gabor; Bitter, Istvan
Acta Chimica Hungarica, 1986 , vol. 121, # 3 p. 263 - 270
反应条件
1: With trichlorophosphate in tetrahydrofuran
T=0°C; Vilsmeier-Haack reaction;
2: With potassium permanganate; sulfuric acid
T=20°C;
参考文献
Jana, Gouranga P.; Ghorai, Binay K.
Letters in Organic Chemistry, 2009 , vol. 6, # 5 p. 372 - 376
