联苯-3,3-二羧酸二甲酯合成路线 （共 14 条）
反应条件
potassium iodide; zinc; Ni(PEt3)2Cl2 in various solvent(s)
T=30°C; 3 h;
参考文献
Takagi; Hayama; Sasaki
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 7 p. 1887 - 1890
反应条件
carbon dioxide; zinc; palladium on activated charcoal in water
T=20°C; Ullmann coupling; P=7500.6 Torr; 96 h;
参考文献
Li, Jin-Heng; Xie, Ye-Xiang; Yin, Du-Lin
Journal of Organic Chemistry, 2003 , vol. 68, # 25 p. 9867 - 9869
反应条件
potassium iodide; niobium bromide; zinc in N,N,N',N',N'',N''-hexamethylphosphoric triamide; N,N-dimethyl-formamide
T=50°C; 3 h;
参考文献
Takagi, Kentaro; Hayama, Naomi; Inokawa, Saburo
Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 12 p. 3691 - 3695
反应条件
tetrabutylammomium bromide; 2,2'-bipyridine*NiBr2 in N,N-dimethyl-formamide
T=20°C; Electrochemical reaction;
参考文献
Sengmany, Stephane; Leonel, Eric; Polissaint, Frantz; Nedelec, Jean-Yves; Pipelier, Muriel; Thobie-Gautier, Christine; Dubreuil, Didier
Journal of Organic Chemistry, 2007 , vol. 72, # 15 p. 5631 - 5636
反应条件
copper(l) chloride in methanol
T=25°C; 4 h;
参考文献
Cheng, Guanjun; Luo, Meiming
European Journal of Organic Chemistry, 2011 , # 13 p. 2519 - 2523
反应条件
N-chloro-succinimide; bis-triphenylphosphine-palladium(II) chloride in various solvent(s)
T=45°C; Homo-coupling reaction; 10 h;
参考文献
Hossain, Kabir M.; Kameyama, Toru; Shibata, Takanori; Takagi, Kentaro
Bulletin of the Chemical Society of Japan, 2001 , vol. 74, # 12 p. 2415 - 2420
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate in 1,4-dioxane
T=20 - 90°C; Suzuki coupling; 14 h;
参考文献
Kusuma, Bhaskar Reddy; Peterson, Laura B.; Zhao, Huiping; Vielhauer, George; Holzbeierlein, Jeffrey; Blagg, Brian S. J.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 18 p. 6234 - 6253
反应条件
1: 81 percent / pyridine
2: 93 percent Chromat. / NiCl2(PPh3)2, Zn, Et4NI / tetrahydrofuran / 1.) r.t., 5 min, 2.) 67 deg C, 10 h
View Scheme
参考文献
Percec, Virgil; Bae, Jin-Young; Zhao, Mingyang; Hill, Dale H.
Journal of Organic Chemistry, 1995 , vol. 60, # 1 p. 176 - 185
反应条件
tributylphosphine; potassium iodide; niobium bromide in N,N,N',N',N'',N''-hexamethylphosphoric triamide; N,N-dimethyl-formamide
T=50°C; 5 h;
参考文献
Takagi, Kentaro; Hayama, Naomi; Inokawa, Saburo
Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 12 p. 3691 - 3695
反应条件
NiCl2((PPh3)P)2; tetraethylammonium iodide; zinc in tetrahydrofuran
1.) r.t., 5 min, 2.) 67 deg C, 10 h;
参考文献
Percec, Virgil; Bae, Jin-Young; Zhao, Mingyang; Hill, Dale H.
Journal of Organic Chemistry, 1995 , vol. 60, # 1 p. 176 - 185
