3-氨基-5-叔丁基噻吩-2-羧酸甲酯合成路线 （共 4 条）
反应条件
potassium carbonate in tetrahydrofuran; methanol Heating;
参考文献
Migianu, Evelyne; Kirsch, Gilbert
Synthesis, 2002 , # 8 p. 1096 - 1100
反应条件
1: 61 percent / POCl3 / 5 h / 60 °C 2: NH2OH*HCl / dimethylformamide / 8 h / 110 °C 3: Ac2O / 18 h / Heating 4: 94 percent / K2CO3 / methanol; tetrahydrofuran / Heating View Scheme
参考文献
Synthesis, , # 8 p. 1096 - 1100
反应条件
1: NH2OH*HCl / dimethylformamide / 8 h / 110 °C 2: Ac2O / 18 h / Heating 3: 94 percent / K2CO3 / methanol; tetrahydrofuran / Heating View Scheme
参考文献
Synthesis, , # 8 p. 1096 - 1100
反应条件
1: With sodium hydroxide in ethanol
2.25 h; Heating / reflux;
2: With hydrogenchloride in ethanol; water
1 h;
参考文献
Dumas, Jacques; Khire, Uday; Lowinger, Timothy B.; Paulsen, Holger; Riedl, Bernd; Scott, William J.; Smith, Roger A.; Wood, Jill E.; Hatoum-Mokdad, Holia; Johnson, Jeffrey; Lee, Wendy; Redman, Aniko; Sibley, Robert; Renick, Joel
Patent: US2007/244120 A1, 2007 ;
Location in patent: Page/Page column 14 ;
US 20070244120 A1
