5-甲基-2-(三氟甲基)呋喃-3-羧酸乙酯合成路线 （共 3 条）
反应条件
toluene-4-sulfonic acid in toluene Heating / reflux;
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1362846 A1, 2003 ;
Location in patent: Page/Page column 125 ;
EP 1362846 A1
反应条件
1: With diisobutylaluminium hydride in tetrahydrofuran; diethyl ether T=0°C; 2: With water; Sodium potassium tartrate in tetrahydrofuran; diethyl ether T=20°C; 18 h;
参考文献
WO2010/59393 A1, ;
Page/Page column 88 ;
WO 2010/059393 A1
反应条件
1: With sodium hydroxide; ethanol; water 0.75 h; Heating / reflux; 2: With hydrogenchloride in water
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1362846 A1, 2003 ;
Location in patent: Page/Page column 125 ;
EP 1362846 A1
