4-氯-1,3-二甲基-1H-吡唑3,4-吡啶-5-羧酸合成路线 （共 4 条）
反应条件
potassium hydroxide in 1,4-dioxane
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 1 p. 29 - 32
反应条件
1: 89 percent / 1 h / 120 °C 2: 77 percent / POCl3 / 18 h / 120 °C 3: 99 percent / potassium hydroxide / H2O; 1,2-dimethoxy-ethane / 18 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 15 p. 4089 - 4100
反应条件
1: 77 percent / POCl3 / 18 h / 120 °C 2: 99 percent / potassium hydroxide / H2O; 1,2-dimethoxy-ethane / 18 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 15 p. 4089 - 4100
反应条件
thionyl chloride T=80°C;
参考文献
Eller, Gernot A.; Holzer, Wolfgang
Molecules, 2007 , vol. 12, # 1 p. 60 - 73
