4-[4-(羟基甲基)苯基]-2-甲基-3-丁炔-2-醇合成路线 （共 6 条）
反应条件
sodium tetrahydroborate in methanol T=-20°C;
参考文献
Klyatskaya, S. V.; Tretyakov, E. V.; Vasilevsky, S. F.
Russian Chemical Bulletin, 2002 , vol. 51, # 1 p. 128 - 134
Izvestiya Akademi Nauk, Seriya Khimicheskaya, 2002 , # 1 p. 122 - 127
反应条件
1: 93 percent / Et3N; PPh3; CuI / Pd(OAc)2 / benzene / 0.67 h / 75 - 80 °C 2: 92 percent / NaBH4 / methanol / -20 °C View Scheme
参考文献
Klyatskaya, S. V.; Tretyakov, E. V.; Vasilevsky, S. F.
Russian Chemical Bulletin, 2002 , vol. 51, # 1 p. 128 - 134
Izvestiya Akademi Nauk, Seriya Khimicheskaya, 2002 , # 1 p. 122 - 127
反应条件
1: 93 percent / Et3N; PPh3; CuI / Pd(OAc)2 / benzene / 0.67 h / 75 - 80 °C 2: 92 percent / NaBH4 / methanol / -20 °C View Scheme
参考文献
Klyatskaya, S. V.; Tretyakov, E. V.; Vasilevsky, S. F.
Russian Chemical Bulletin, 2002 , vol. 51, # 1 p. 128 - 134
Izvestiya Akademi Nauk, Seriya Khimicheskaya, 2002 , # 1 p. 122 - 127
反应条件
1: 66 percent / KOH / benzene / 2 h / Heating 2: 74 percent / pyridinium chlorochromate / CH2Cl2 / 1 h / -20 °C View Scheme
参考文献
Klyatskaya, S. V.; Tretyakov, E. V.; Vasilevsky, S. F.
Russian Chemical Bulletin, 2002 , vol. 51, # 1 p. 128 - 134
Izvestiya Akademi Nauk, Seriya Khimicheskaya, 2002 , # 1 p. 122 - 127
反应条件
potassium hydroxide in benzene 2 h; Heating;
参考文献
Russian Chemical Bulletin, , vol. 51, # 1 p. 128 - 134
Izvestiya Akademi Nauk, Seriya Khimicheskaya, , # 1 p. 122 - 127
反应条件
1: 66 percent / KOH / benzene / 2 h / Heating
2: 74 percent / pyridinium chlorochromate / CH2Cl2 / 1 h / -20 °C
3: 93 percent / Et3N; PPh3; CuI / Pd(OAc)2 / benzene / 6.5 h / 75 - 80 °C
View Scheme
参考文献
Klyatskaya, S. V.; Tretyakov, E. V.; Vasilevsky, S. F.
Russian Chemical Bulletin, 2002 , vol. 51, # 1 p. 128 - 134
Izvestiya Akademi Nauk, Seriya Khimicheskaya, 2002 , # 1 p. 122 - 127
