4,7-二溴-3-甲氧基-2-萘羧酸甲酯合成路线 （共 3 条）
反应条件
potassium carbonate in acetone T=60°C; 10 h;
参考文献
Institute Of Pharmacology And Toxicology Academy Of Militaty Medical Sciences P.L.A.; LI, Song; ZHONG, Wu; LIU, Ping; XIAO, Junhai; ZHENG, Zhibing; XIE, Yunde; ZHAO, Guoming; WANG, Xiaokui; WANG, Lili; LI, Xingzhou; ZHOU, Xinbo
Patent: EP2573067 A1, 2013 ;
Location in patent: Paragraph 0055; 0056; 0119; 0120 ;
反应条件
18-crown-6 ether; potassium carbonate in tetrahydrofuran T=20°C;
参考文献
Verga, Daniela; Doria, Filippo; Mella, Mariella; Freccero, Mauro
Journal of Organic Chemistry, 2009 , vol. 74, # 15 p. 5311 - 5319
反应条件
1: acetic acid; bromine / 10 h / 20 - 125 °C 2: potassium carbonate / acetone / 10 h / 60 °C View Scheme
参考文献
Institute Of Pharmacology And Toxicology Academy Of Militaty Medical Sciences P.L.A.; LI, Song; ZHONG, Wu; LIU, Ping; XIAO, Junhai; ZHENG, Zhibing; XIE, Yunde; ZHAO, Guoming; WANG, Xiaokui; WANG, Lili; LI, Xingzhou; ZHOU, Xinbo
Patent: EP2573067 A1, 2013 ;
