4-(4-(1-羟基乙基)-2-甲氧基-5-硝基苯氧基)丁酸合成路线 （共 10 条）
反应条件
lithium hydroxide monohydrate in methanol
反应条件
water; trifluoroacetic acid T=80°C; 42 h;
参考文献
US8343710 B1, ;
Page/Page column 14; 16 ;
反应条件
1: K2CO3 / dimethylformamide / Ambient temperature 2: 93 percent / NaBH4 / methanol / 0 °C 3: 88 percent / HNO3 / 0 °C 4: 93 percent / NaOH / tetrahydrofuran; H2O / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 38, # 45 p. 7851 - 7852
反应条件
sodium hydroxide in tetrahydrofuran; water Heating;
参考文献
Tetrahedron Letters, , vol. 38, # 45 p. 7851 - 7852
反应条件
1: 93 percent / NaBH4 / methanol / 0 °C 2: 88 percent / HNO3 / 0 °C 3: 93 percent / NaOH / tetrahydrofuran; H2O / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 38, # 45 p. 7851 - 7852
反应条件
1: 66 percent / aq. HNO3 / acetic anhydride / 2.5 h / 0 °C 2: NaBH4 / tetrahydrofuran; methanol / 15 h / Ambient temperature 3: 16.61 g / NaOH / methanol; H2O; tetrahydrofuran / 7 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 62, # 8 p. 2370 - 2380
反应条件
1: NaBH4 / tetrahydrofuran; methanol / 15 h / Ambient temperature 2: 16.61 g / NaOH / methanol; H2O; tetrahydrofuran / 7 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 62, # 8 p. 2370 - 2380
反应条件
sodium tetrahydroborate; sodium hydrogencarbonate in ethanol pH=9 - 11; 3 h;
参考文献
Journal of the American Chemical Society, , vol. 134, # 40 p. 16558 - 16561
反应条件
1: sodium tetrahydroborate 2: water; sodium hydroxide View Scheme
参考文献
Soft Matter, , vol. 7, # 10 p. 4881 - 4887
反应条件
1: 88 percent / HNO3 / 0 °C 2: 93 percent / NaOH / tetrahydrofuran; H2O / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 38, # 45 p. 7851 - 7852
