N-(二苯基亚甲基)-N-[(5-甲基吡啶-3-基)甲基]胺合成路线 （共 8 条）
反应条件
acetic acid in methanol T=60 - 80°C;
参考文献
Pandey, Shailendra; Srivastava
Medicinal Chemistry Research, 2011 , vol. 20, # 7 p. 1091 - 1101
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 15 p. 4359 - 4363
参考文献
Yeagley, Andrew A.; Chruma, Jason J.
Organic Letters, 2007 , vol. 9, # 15 p. 2879 - 2882
反应条件
1: 99 percent / iodotrimethylsilane / CH2Cl2 / 20 °C 2: 92 percent / benzene / Heating View Scheme
参考文献
Organic Letters, , vol. 9, # 15 p. 2879 - 2882
反应条件
1.1: NaOH / acetone / 20 °C 1.2: 3.630 g / triethylamine / CH2Cl2 / 24 h 2.1: 99 percent / iodotrimethylsilane / CH2Cl2 / 20 °C 3.1: 92 percent / benzene / Heating View Scheme
参考文献
Organic Letters, , vol. 9, # 15 p. 2879 - 2882
反应条件
1: 2.4 M n-BuLi, diisopropylamine / tetrahydrofuran; hexane / -78 - -45 °C 2: 1.) 10percent aq. HCl, 2.) K2CO3, 40percent aq. KOH / 1.) THF, hexane, water, 15-20 min, room temp., 2.) water, pH 10-12 View Scheme
参考文献
Deo, Niranjan M.; Crooks, Peter A.
Tetrahedron Letters, 1996 , vol. 37, # 8 p. 1137 - 1140
反应条件
1: 2.4 M n-BuLi, diisopropylamine / tetrahydrofuran; hexane / -78 - -45 °C 2: 1.) 10percent aq. HCl, 2.) K2CO3, 40percent aq. KOH / 1.) THF, hexane, water, 15-20 min, room temp., 2.) water, pH 10-12 View Scheme
参考文献
Deo, Niranjan M.; Crooks, Peter A.
Tetrahedron Letters, 1996 , vol. 37, # 8 p. 1137 - 1140
反应条件
1: 2.4 M n-BuLi, diisopropylamine / tetrahydrofuran; hexane / -78 - -45 °C 2: 1.) 10percent aq. HCl, 2.) K2CO3, 40percent aq. KOH / 1.) THF, hexane, water, 15-20 min, room temp., 2.) water, pH 10-12 View Scheme
参考文献
Deo, Niranjan M.; Crooks, Peter A.
Tetrahedron Letters, 1996 , vol. 37, # 8 p. 1137 - 1140
