1: 1) LDA, TMSCl, 2) Pd(OAc)2 / 1) THF, -80 deg C, 1 h, 2) CH3CN, r.t., 5 h 2: 1) HMDS, n-BuLi, 2) AcOH / 1) THF/HMPT, -80 deg C, 1 h, 2) -80 deg C View Scheme

<b>Multi-step reaction with 3 steps<br /> </b>1: boron trifluoride etherate / CH₂Cl₂ / -78 deg C, then room temperature<br />2: 100.4 mg / trifluoroacetic acid / CH₂Cl₂ / 4 h / Ambient temperature<br />3: 69 percent / hydrogen / 5 percent Pd-CaCO₃ / toluene / 760 Torr<br /> <br /> &nbsp;