25-去乙酰氧基-25-羟基利福霉素合成路线 （共 4 条）
反应条件
sodium hydroxide in 1,4-dioxane
参考文献
Brufani, Mario; Cellai, Luciano; Bartolini, Barbara; Medici, Ilaria; Lagrasta, Bianca Maria
Patent: US2010/168129 A1, 2010 ;
Location in patent: Page/Page column 10 ;
反应条件
1: With propionaldehyde dimethyl acetal; sulfuric acid; sodium carbonate T=20°C; 0.833333 h; 2: With sodium hydroxide in methanol T=20°C; 18 h; 3: With citric acid pH=4;
参考文献
van Duzer, John H.; Michaelis, Arthur F.; Geiss, William B.; Stafford, Douglas G.; Raker, Joseph; Yu, Xiang Y.; Siedlecki, James M.; Yang, Yingfei
Patent: US2005/197333 A1, 2005 ;
Location in patent: Page/Page column 44 ;
参考文献
Kump; Bickel
Helvetica Chimica Acta, 1973 , vol. 56, # 7 p. 2323 - 2347
反应条件
1: CuSO4
2: CrO3, Py / CH2Cl2
View Scheme
参考文献
Kump; Bickel
Helvetica Chimica Acta, 1973 , vol. 56, # 7 p. 2323 - 2347
