6-氯-3,4-二氢-2(1H)-萘酮合成路线 （共 13 条）
反应条件
1: carbonic acid dimethyl ester With sodium hydride in toluene
1 h; Heating / reflux;
2: 6-chloro-3,4-dihydro-2(1H)-naphthalenone in toluene
24 h; Heating / reflux;
3: With acetic acid in toluene
T=0°C;
参考文献
SANOFI-AVENTIS
Patent: US2007/105932 A1, 2007 ;
Location in patent: Page/Page column 5 ;
US 20070105932 A1
反应条件
sodium hydride
0.75 h; Heating;
参考文献
Pendergast; Johnson; Dickerson; Dev; Duch; Ferone; Hall; Humphreys; Kelly; Wilson
Journal of Medicinal Chemistry, 1993 , vol. 36, # 16 p. 2279 - 2291
反应条件
toluene-4-sulfonic acid
参考文献
McNally, James J.; Youngman, Mark A.; Lovenberg, Timothy W.; Nepomuceno, Diane H.; Wilson, Sandy J.; Dax, Scott L.
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 3 p. 213 - 216
