5-氯-3,4-二氢-1H-2-萘酮合成路线 （共 7 条）
反应条件
aluminium trichloride in dichloromethane Cyclization;
参考文献
Nevy, John B.; Hawkinson, David C.; Blotny, Grzegorz; Yao, Xudong; Pollack, Ralph M.
Journal of the American Chemical Society, 1997 , vol. 119, # 52 p. 12722 - 12726
反应条件
titanium tetrachloride in dichloromethane T=0 - 20°C; Friedel Crafts reaction; 8 h;
参考文献
Hon, Yung-Son; Devulapally, Rammohan
Tetrahedron Letters, 2009 , vol. 50, # 41 p. 5713 - 5715
反应条件
titanium tetrachloride in dichloromethane T=-78 - 20°C; 5 h;
参考文献
Hon, Yung-Son; Devulapally, Rammohan
Tetrahedron Letters, 2009 , vol. 50, # 23 p. 2831 - 2834
反应条件
titanium tetrachloride in dichloromethane T=-78 - 20°C; 5 h;
参考文献
Tetrahedron Letters, , vol. 50, # 23 p. 2831 - 2834
反应条件
aluminium trichloride in dichloromethane 2 h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
European Journal of Medicinal Chemistry, , vol. 28, # 9 p. 693 - 701
反应条件
1: thionyl chloride / 1,2-dichloro-ethane / 4 h / Heating 2: 4.3 g / AlCl3 / CH2Cl2 / -5 - 5 °C View Scheme
参考文献
Synthetic Communications, , vol. 33, # 13 p. 2215 - 2227
反应条件
1: TiCl4 / CH2Cl2; tetrahydrofuran / 2 h / 0 °C
2: Ph3COH, TFA / 48 h / Ambient temperature
View Scheme
参考文献
Ellingboe, John W.; Lombardo, Louis J.; Alessi, Thomas R.; Nguyen, Thomas T.; Guzzo, Frieda; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 17 p. 2485 - 2493
