1.1: calcium carbonate; palladium diacetate / methanol / 4 h / 60 °C 1.2: 20 °C 2.1: (R)-(S)-Cy2PF-PCy2; copper diacetate; DEMS / tetrahydrofuran; toluene; tert-butyl alcohol / 3 h / 20 °C / |Inert atmosphere 3.1: pyridinium chlorochromate / dichloromethane / 3 h / 20 °C / |Inert atmosphere View Scheme

[{Rh(OH)(cod)}2]; triethylamine in tetrahydrofuran T=100°C; 15 h;

1.1: calcium carbonate; palladium diacetate / methanol / 4 h / 60 °C 1.2: 20 °C 2.1: copper diacetate; DEMS; josiphos / tetrahydrofuran; toluene; tert-butyl alcohol / 3 h / 20 °C / |Inert atmosphere 3.1: sodium tris(acetoxy)borohydride; acetic acid / 1,2-dichloro-ethane / 72 h / 20 °C / |Inert atmosphere View Scheme

1: With palladium diacetate; calcium carbonate in methanol T=60°C; 4 h; 2: With hydrogen in methanol T=20°C;

palladium diacetate; calcium carbonate in methanol T=60°C; Heck Reaction;

1.1: calcium carbonate; palladium diacetate / methanol / 4 h / 60 °C 1.2: 20 °C 2.1: copper diacetate; DEMS; josiphos / tetrahydrofuran; toluene; tert-butyl alcohol / 3 h / 20 °C / |Inert atmosphere 3.1: pyridinium chlorochromate / dichloromethane / 3 h / 20 °C / |Inert atmosphere View Scheme