2,5-双(三甲基硅基)二溴噻吩合成路线 （共 6 条）
反应条件
1: 2,3,4,5-tetrabromothiophene With n-butyllithium in tetrahydrofuran; n-heptane T=-78°C; 1 h; Inert atmosphere; 2: chloro-trimethyl-silane in tetrahydrofuran; n-heptane T=-78 - 20°C; 16 h; Inert atmosphere; regioselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 351, # 10 p. 1595 - 1609
反应条件
1: 2,5-dibromothiophene With lithium diisopropyl amide in tetrahydrofuran T=-78°C; 2: chloro-trimethyl-silane in tetrahydrofuran
参考文献
Tetrahedron Letters, , vol. 42, # 10 p. 2039 - 2041
反应条件
1: 3,4-Dibromo-thiophene With lithium diisopropyl amide in diethyl ether; hexane T=0°C; 2 h; 2: chloro-trimethyl-silane in diethyl ether; hexane T=-78 - 20°C;
参考文献
Letters in Organic Chemistry, , vol. 6, # 6 p. 474 - 477
反应条件
1: 3,5-dibromo-2-(trimethylsilyl)thiophene With lithium diisopropyl amide in tetrahydrofuran T=-78°C; 2: chloro-trimethyl-silane in tetrahydrofuran
参考文献
Tetrahedron Letters, , vol. 42, # 10 p. 2039 - 2041
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=-80°C; 2: With N-fluoro-N-(phenylsulfonyl)benzene-sulfonamide in tetrahydrofuran; hexane T=-80°C; Further stages.;
参考文献
Sakamoto; Komatsu; Suzuki
Journal of the American Chemical Society, 2001 , vol. 123, # 19 p. 4643 - 4644
反应条件
1: With n-butyllithium in tetrahydrofuran
T=-78°C;
2: With water in tetrahydrofuran
参考文献
Lukevics, Edmunds; Arsenyan, Pavel; Belyakov, Sergey; Popelis, Juris; Pudova, Olga
Tetrahedron Letters, 2001 , vol. 42, # 10 p. 2039 - 2041
