N-叔-丁基氧羰基-D-核-植物鞘氨醇合成路线 （共 2 条）
参考文献
Mormeneo, David; Casas, Josefina; Llebaria, Amadeu; Delgado, Antonio
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 23 p. 3769 - 3777
反应条件
1: 97 percent / pyridine / dimethylformamide / 0.5 h / -40 °C
2: 99 percent / Ac2O; DMSO / 16 h / 20 °C
3: 89 percent / KHMDS / tetrahydrofuran; toluene / 3 h / -68 - -20 °C
4: 91 percent / HCOOH; TEA / Pd(OAc)2(triphenylphosphine)2 / dimethylformamide / 4 h / 60 °C
5: 100 percent / TBAF; AcOH / tetrahydrofuran / 1 h / 0 °C
View Scheme
参考文献
Van Den Berg, Richard J.B.H.N.; Korevaar, Cornelis G.N.; Van Der Marel, Gijsbert A.; Overkleeft, Herman S.; Van Boom, Jacques H.
Tetrahedron Letters, 2002 , vol. 43, # 46 p. 8409 - 8412
