in diethyl ether; dichloromethane T=0 - 20°C; 2 h;

1.1: sulfuryl dichloride / methanol; dichloromethane / 7 h / -5 - 0 °C / Large scale reaction 2.1: sodium bromide / N,N-dimethyl-formamide / 30 h / 35 °C / Inert atmosphere; Large scale reaction 3.1: bis(acetylacetonate)oxovanadium / ethanol / 26.5 h / 30 - 40 °C / Large scale reaction 4.1: triethylsilane; trifluoroacetic acid / 27 h / 50 - 88 °C / Inert atmosphere; Large scale reaction 4.2: 50 °C / pH 10 - 11 / Large scale reaction 5.1: tris-(dibenzylideneacetone)dipalladium(0); 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; sodium hydroxide / water; toluene 6.1: methoxybenzene; trifluoroacetic acid / Heating View Scheme

1: sulfuryl dichloride / methanol; dichloromethane / 7 h / -5 - 0 °C / Large scale reaction 2: sodium bromide / N,N-dimethyl-formamide / 30 h / 35 °C / Inert atmosphere; Large scale reaction 3: bis(acetylacetonate)oxovanadium / ethanol / 26.5 h / 30 - 40 °C / Large scale reaction View Scheme

1: titanium tetraethoxide / tetrahydrofuran / 18 h / 20 °C 2: L-Selectridereg; / tetrahydrofuran / 18 h / -45 - 20 °C 3: hydrogenchloride / methanol; 1,4-dioxane / 18 h / 0 - 20 °C View Scheme