(乙氧基羰基甲基)三苯基氯化膦合成路线 （共 18 条）
反应条件
in acetonitrile 48 h; Heating;
参考文献
Russian Journal of Organic Chemistry, , vol. 39, # 4 p. 536 - 541
反应条件
1-ethyl-2-methyl-4-nitro-1H-imidazole-5-carbonyl chloride in toluene 3 h; Ambient temperature; Yield given;
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 5 p. 629 - 640
反应条件
in benzene 1.) 5-8 deg C, 10 min, 2.) room temperature, 2 h;
参考文献
Synthetic Communications, , vol. 16, # 3 p. 299 - 308
反应条件
in toluene 3 h; Ambient temperature; Yields of byproduct given;
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 5 p. 629 - 640
反应条件
1: potassium hydroxide / ethanol / 1.5 h / 80 °C 2: potassium carbonate; potassium iodide / acetone / 22 h / 60 °C 3: ethylene glycol / 6 h / Reflux 4: potassium carbonate; potassium iodide / acetone / 5 h / 20 °C 5: Grubb's 2nd generation catalyst / dichloromethane / 2 h / 45 °C / Inert atmosphere View Scheme
参考文献
Liu, Guang-Lu; Hao, Bing; Liu, Shao-Peng; Wang, Gao-Xue
European Journal of Medicinal Chemistry, 2012 , vol. 54, p. 582 - 590
反应条件
potassium hydroxide in ethanol T=80°C; 1.5 h;
参考文献
Liu, Guang-Lu; Hao, Bing; Liu, Shao-Peng; Wang, Gao-Xue
European Journal of Medicinal Chemistry, 2012 , vol. 54, p. 582 - 590
反应条件
aluminum oxide T=20°C; 48 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Texier-Boullet, F.; Villemin, D.; Ricard, M.; Moison, H.; Foucaud, A.
Tetrahedron, 1985 , vol. 41, # 7 p. 1259 - 1266
反应条件
1: potassium hydroxide / ethanol / 1.5 h / 80 °C 2: potassium carbonate; potassium iodide / acetone / 5 h / 20 °C View Scheme
参考文献
Liu, Guang-Lu; Hao, Bing; Liu, Shao-Peng; Wang, Gao-Xue
European Journal of Medicinal Chemistry, 2012 , vol. 54, p. 582 - 590
反应条件
1: Ph3P(1+)CH2COOEt(Cl(1-)) With sodium hydride in tetrahydrofuran; mineral oil 1 h; Inert atmosphereReflux; 2: 4-monomethoxy-1-naphthaldehyde in tetrahydrofuran; mineral oil T=0 - 20°C; Wittig reaction; Inert atmosphere; 3: With sulfuric acid in acetone 6 h; Reflux;
参考文献
Voelker, Troy; Xia, Haiji; Fandrick, Keith; Johnson, Robert; Janowsky, Aaron; Cashman, John R.
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 5 p. 2047 - 2068
反应条件
potassium hydroxide in water
参考文献
Spencer, Elinor C.; Baby Mariyatra, Mahimaidoss; Howard, Judith A.K.; Kenwright, Alan M.; Panchanatheswaran, Krishnaswamy
Journal of Organometallic Chemistry, 2007 , vol. 692, # 5 p. 1081 - 1086
