2-氨基-5,6-二氢-4H-苯并噻唑-7-酮合成路线 （共 8 条）
反应条件
pyridine in methanol 3.5 h; Reflux;
参考文献
McIntyre, Neil A.; McInnes, Campbell; Griffiths, Gary; Barnett, Anna L.; Kontopidis, George; Slawin, Alexandra M. Z.; Jackson, Wayne; Thomas, Mark; Zheleva, Daniella I.; Wang, Shudong; Blake, David G.; Westwood, Nicholas J.; Fischer, Peter M.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 5 p. 2136 - 2145
反应条件
in N-methyl-acetamide
参考文献
Yungjin Pharmaceutical Co., Ltd.
Patent: US6043373 A1, 2000 ;
反应条件
thiourea in tetrahydrofuran; 1,4-dioxane; water
反应条件
in ethanol T=20°C; 2 h; Heating / reflux;
参考文献
US2007/244104 A1, ;
Page/Page column 14 ;
反应条件
1-methyl-1H-imidazole in water; isopropyl alcohol T=20°C; 2 h;
参考文献
Meshram; Thakur, Pramod B.; Madhu Babu; Bangade, Vikas M.
Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5265 - 5269
反应条件
1: bromine; acetic acid / 3 h / 20 °C / Cooling with ice 2: ethanol / Reflux View Scheme
反应条件
sodium hydroxide 1) EtOH, 7 d, 20 deg C, 2) 20 min, RT; Yield given. Multistep reaction;
参考文献
Monatshefte fuer Chemie, , vol. 124, # 6/7 p. 763 - 774
反应条件
n-Butyl nitrite; copper dichloride in acetonitrile 0.333333 h; Heating;
参考文献
Stepanov; Ivanov; Ivanova
Russian Journal of General Chemistry, 2000 , vol. 70, # 5 p. 784 - 787
