(R)-(+)-1,1,1-三氟庚基-2-醇合成路线 （共 6 条）
反应条件
sodium hydroxide; potassium dihydrogenphosphate; lipase MY (from Candida rugosa) T=38°C; 6 h; Yield given;
参考文献
Journal of Fluorine Chemistry, , vol. 84, # 1 p. 19 - 23
反应条件
1: NaBH4 / H2O; diethyl ether / Ambient temperature 2: pyridine / CH2Cl2 3: lipase MY (from Candida rugosa), aq. KH2PO4, NaOH / 6 h / 38 °C View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 84, # 1 p. 19 - 23
反应条件
1: diethyl ether / 0.5 h / Ambient temperature 2: NaBH4 / H2O; diethyl ether / Ambient temperature 3: pyridine / CH2Cl2 4: lipase MY (from Candida rugosa), aq. KH2PO4, NaOH / 6 h / 38 °C View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 84, # 1 p. 19 - 23
反应条件
1: pyridine / CH2Cl2 2: lipase MY (from Candida rugosa), aq. KH2PO4, NaOH / 6 h / 38 °C View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 84, # 1 p. 19 - 23
反应条件
in diethyl ether; hexane -20 deg C to room temp.; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 31, # 48 p. 7031 - 7034
反应条件
in diethyl ether 1.) -70 deg C, 1.5 h, 2.) r.t., overnight;
参考文献
Journal of Fluorine Chemistry, , vol. 84, # 1 p. 19 - 23
