1: cis-4-aminocyclohexane carboxylic acid With thionyl chloride in dichloromethane T=20°C; 0.666667 h; 2: methanol 2.25 h; Heating / reflux; 3: With sodium hydroxide in water

in methanol; hexane; dichloromethane

1: 84 percent / hydrogen / rhodium on carbon / H2O / 100 °C / 83600 Torr 2: 90 percent / conc. sulfuric acid / 48 h / Heating View Scheme