hydrogenchloride; palladium 10 on activated carbon; hydrogen in methanol; water T=20°C; P=11251.1 Torr; 3 h;

<b>Multi-step reaction with 13 steps<br /> </b>1: N,N- diisopropylethylamine; sodium iodide / DMFA / 3.5 h / 100 &deg;C<br />2: phosphoryl chloride / 4 h / 25 - 35 &deg;C<br />3: bromine / dichloromethane / 2.5 h / 0 &deg;C<br />4: dichloromethane; toluene / 16 h / |Reflux<br />5: sodium hydroxide / methanol; water / 3 h / 40 &deg;C<br />6: triethylamine; hydrogen / methanol / 2 h / 70 &deg;C / 6080.41 - 7600.51 Torr / |Autoclave; |Inert atmosphere<br />7: N,N- diisopropylethylamine; diphenyl phosphoryl azide / toluene / 1 h / 70 &deg;C<br />8: 10 h / 95 &deg;C<br />9: DMFA / 20 h / 120 &deg;C / |Inert atmosphere<br />10: hydrogen; palladium on activated charcoal / methanol / 3 h / 20 &deg;C / 11251.1 Torr<br />11: toluene / 18 h / |Reflux<br />12: sodium hydrogencarbonate / 1,4-dioxane / 2 h / 20 &deg;C<br />13: sodium hydroxide; hydrogen peroxide / dimethyl sulfoxide / 12 h / 20 - 25 &deg;C<br /> <br /> &nbsp;