bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine 0.116667 h; Ambient temperature;

1: 81 percent / aq. NH3 / 1.5 h / 50 - 60 °C 2: 79 percent / pyridine, trifluoroacetic anhydride / dioxane / Ambient temperature 3: 85 percent / triethylamine, Pd(PPh3)2Cl2, CuI / 0.12 h / Ambient temperature View Scheme

1: 79 percent / pyridine, trifluoroacetic anhydride / dioxane / Ambient temperature 2: 85 percent / triethylamine, Pd(PPh3)2Cl2, CuI / 0.12 h / Ambient temperature View Scheme

1: 80 percent / 1.) I2, conc. H2SO4, 2.) aq. NH3, 3.) (CF3CO)2O, pyridine / 1) 85-90 deg C, 24 h; 2) 50-60 deg C, 1.5 h; 3) dioxane, rt, overnight 2: 85 percent / triethylamine, Pd(PPh3)2Cl2, CuI / 0.12 h / Ambient temperature View Scheme