4-氯-2-甲基-6-硝基苯酚合成路线 (共 6 条)
反应条件
nitric acid; acetic acid T=5°C; 0.666667 h;
参考文献
Gao, Mingzhang; Wang, Min; Hutchins, Gary D.; Zheng, Qi-Huang
European Journal of Medicinal Chemistry, 2008 , vol. 43, # 7 p. 1570 - 1574
反应条件
nitric acid in acetic anhydride T=-60°C; 0.166667 h; Title compound not separated from byproducts;
参考文献
Clewley, Robin G.; Cross, Gordon G.; Fischer, Alfred; Henderson, George N.
Tetrahedron, 1989 , vol. 45, # 5 p. 1299 - 1310
反应条件
nitric acid; acetic acid
参考文献
Bures
Chemicke Listy, vol. 21, p. 161
Chem. Zentralbl., 1927 , vol. 98, # II p. 1344
反应条件
(i) (reduction), (ii) (nitration); Multistep reaction;
参考文献
Deorha,D.S.; Sareen,S.P.
Journal of the Indian Chemical Society, 1964 , vol. 41, # 12 p. 837 - 840
参考文献
Zincke
Justus Liebigs Annalen der Chemie, 1918 , vol. 417, p. 231
反应条件
hydrogen; nickel in ethanol
P=2896.11 Torr; 7 h;
参考文献
Gao, Mingzhang; Wang, Min; Hutchins, Gary D.; Zheng, Qi-Huang
European Journal of Medicinal Chemistry, 2008 , vol. 43, # 7 p. 1570 - 1574