4-氨基-2,5-二甲氧基苯胺合成路线 （共 10 条）
反应条件
hydrogen; platinum on activated charcoal in ethanol Reduction; P=1520.1 Torr; 15 h;
参考文献
Miller, Scott E.; Lukas, Aaron S.; Marsh, Emily; Bushard, Patrick; Wasielewski, Michael R.
Journal of the American Chemical Society, 2000 , vol. 122, # 32 p. 7802 - 7810
反应条件
hydrogen; palladium(II) oxide hydrate in methanol; ethyl acetate T=25°C; P=45.0045 Torr; 6 h;
参考文献
Wang, Christy; Sperry, Jonathan
Tetrahedron, 2013 , vol. 69, # 23 p. 4563 - 4577
反应条件
sodium tetrahydroborate in tetrahydrofuran; methanol T=20°C; 1 h;
参考文献
Wang, Gui-Tao; Zhao, Xin; Li, Zhan-Ting
Tetrahedron, 2011 , vol. 67, # 1 p. 48 - 57
反应条件
sodium dithionite; nitric acid 1.) glacial acetic acid, 80-90 deg C, 5 min, 2.) THF, MeOH, reflux, 1 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Shen, De-Qing; Wu, Ning; Li, Yan-Ping; Wu, Zu-Ping; Zhang, Hong-Bin; Huang, Zhi-Shu; Gu, Lian-Quan; An, Lin-Kun
Australian Journal of Chemistry, 2010 , vol. 63, # 7 p. 1116 - 1121
反应条件
1: 35 percent / acetic acid; nitric acid / 0.5 h / 80 °C 2: hydrogen / Pd/C / tetrahydrofuran / 7 h / 20 °C / 760.05 Torr View Scheme
参考文献
Wang, Gui-Tao; Zhao, Xin; Li, Zhan-Ting
Tetrahedron, 2011 , vol. 67, # 1 p. 48 - 57
反应条件
1: tin (II) chloride dihydrate / ethyl acetate / 2 h / Reflux 2: sodium tetrahydroborate / tetrahydrofuran; methanol / 1 h / 20 °C View Scheme
参考文献
Wang, Gui-Tao; Zhao, Xin; Li, Zhan-Ting
Tetrahedron, 2011 , vol. 67, # 1 p. 48 - 57
反应条件
1: ethanol; iron; ammonium chloride / 5 h / Reflux 2: triethylamine / chloroform / 0 - 20 °C 3: nitric acid; acetic acid / chloroform / 0.25 h / 0 °C 4: tin (II) chloride dihydrate / ethyl acetate / 2 h / Reflux 5: sodium tetrahydroborate / tetrahydrofuran; methanol / 1 h / 20 °C View Scheme
参考文献
Wang, Gui-Tao; Zhao, Xin; Li, Zhan-Ting
Tetrahedron, 2011 , vol. 67, # 1 p. 48 - 57
反应条件
1: nitric acid; acetic acid / chloroform / 0.25 h / 0 °C 2: tin (II) chloride dihydrate / ethyl acetate / 2 h / Reflux 3: sodium tetrahydroborate / tetrahydrofuran; methanol / 1 h / 20 °C View Scheme
参考文献
Wang, Gui-Tao; Zhao, Xin; Li, Zhan-Ting
Tetrahedron, 2011 , vol. 67, # 1 p. 48 - 57
反应条件
1: triethylamine / chloroform / 0 - 20 °C 2: nitric acid; acetic acid / chloroform / 0.25 h / 0 °C 3: tin (II) chloride dihydrate / ethyl acetate / 2 h / Reflux 4: sodium tetrahydroborate / tetrahydrofuran; methanol / 1 h / 20 °C View Scheme
参考文献
Wang, Gui-Tao; Zhao, Xin; Li, Zhan-Ting
Tetrahedron, 2011 , vol. 67, # 1 p. 48 - 57
参考文献
Siefken
Justus Liebigs Annalen der Chemie, 1949 , vol. 562, p. 75,1114
