2-叔丁基-1,3-苯并噻唑合成路线 （共 41 条）
反应条件
tert.-butyl lithium in tetrahydrofuran
0.0833333 h;
参考文献
Katritzky, Alan R.; Kuzmierkiewicz, Wojciech; Aurrecoechea, Jose M.
Journal of Organic Chemistry, 1987 , vol. 52, # 5 p. 844 - 849
反应条件
1-methyl-pyrrolidin-2-one; potassium carbonate
T=100°C; Hydrolysis; cyclization; 2 h;
参考文献
Chakraborti, Asit K.; Nayak, Mrinal K.; Sharma, Lalima
Journal of Organic Chemistry, 1999 , vol. 64, # 21 p. 8027 - 8230
反应条件
1-methyl-pyrrolidin-2-one; potassium carbonate
T=100°C; Hydrolysis; cyclization; 1.5 h;
参考文献
Chakraborti, Asit K.; Nayak, Mrinal K.; Sharma, Lalima
Journal of Organic Chemistry, 1999 , vol. 64, # 21 p. 8027 - 8230
反应条件
1-methyl-pyrrolidin-2-one; potassium carbonate
T=100°C; Hydrolysis; cyclization; 2 h;
参考文献
Chakraborti, Asit K.; Nayak, Mrinal K.; Sharma, Lalima
Journal of Organic Chemistry, 1999 , vol. 64, # 21 p. 8027 - 8230
反应条件
tert.-butyl lithium in tetrahydrofuran
0.0833333 h;
参考文献
Katritzky, Alan R.; Kuzmierkiewicz, Wojciech; Aurrecoechea, Jose M.
Journal of Organic Chemistry, 1987 , vol. 52, # 5 p. 844 - 849
反应条件
in dimethylsulfoxide-d6; dichloromethane
T=35 - 40°C; 72 h; Irradiation;
参考文献
Russell, Glen A.; Ngoviwatchai, Preecha; Tashtoush, Hasan I.; Pla-Dalmau, Anna; Khanna, Rajive K.
Journal of the American Chemical Society, 1988 , vol. 110, # 11 p. 3530 - 3538
反应条件
T=240°C; P=12928.7 Torr; 0.0666667 h; microwave irradiation;
参考文献
Kamila, Sukanta; Zhang, Hongming; Biehl, Edward R.
Heterocycles, 2005 , vol. 65, # 9 p. 2119 - 2126
反应条件
1: 70 percent / Lawesson reagent
2: 88 percent / Cs2CO3 / o-biphenylP(t-Bu)2; Pd2dba3 / dioxane / 18 h / 80 °C
View Scheme
参考文献
Benedi, Carolina; Bravo, Fernando; Uriz, Pedro; Fernandez, Elena; Claver, Carmen; Castillon, Sergio
Tetrahedron Letters, 2003 , vol. 44, # 32 p. 6073 - 6077
反应条件
1: 70 percent / Lawesson reagent
2: 88 percent / Cs2CO3 / o-biphenylP(t-Bu)2; Pd2dba3 / dioxane / 18 h / 80 °C
View Scheme
参考文献
Benedi, Carolina; Bravo, Fernando; Uriz, Pedro; Fernandez, Elena; Claver, Carmen; Castillon, Sergio
Tetrahedron Letters, 2003 , vol. 44, # 32 p. 6073 - 6077
反应条件
1: 79 percent / potassium carbonate / acetone / 12 h / 25 °C
2: 1.) LDA / 1.) THF, hexane, -78 deg C, 2 h, 2.) THF, hexane, -78 deg C, 4 h
3: 96 percent / tetrahydrofuran / 0.08 h / -78 °C
View Scheme
参考文献
Katritzky, Alan R.; Kuzmierkiewicz, Wojciech; Aurrecoechea, Jose M.
Journal of Organic Chemistry, 1987 , vol. 52, # 5 p. 844 - 849
