(R)-(-)-2-甲氧基-2-苯乙醇合成路线 （共 46 条）
反应条件
1: 85 percent / t-BuOK / acetonitrile / 12 h / 20 °C 2: 100 percent / TBAF / acetonitrile / 4 h / 20 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 14, # 4 p. 503 - 510
反应条件
2: 89 percent / LiAlH4 / diethyl ether / 2 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 12 p. 2238 - 2243
反应条件
immobilized Candida antarctica Lipase B in tetrahydrofuran T=30°C; 32 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 13, # 10 p. 1091 - 1096
反应条件
1: Pb(OAc)4 / benzene / 20 °C 2: NaBH4 / methanol / 0 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 16, # 11 p. 1897 - 1900
反应条件
1: FeCl3*6H2O / CH2Cl2 / 20 °C 2: Pb(OAc)4 / benzene / 20 °C 3: NaBH4 / methanol / 0 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 16, # 11 p. 1897 - 1900
反应条件
1.1: K-selectride; 18-crown-6 / tetrahydrofuran / 4.5 h / -78 °C 1.2: NaH / dimethylformamide / 20 °C 2.1: FeCl3*6H2O / CH2Cl2 / 20 °C 3.1: Pb(OAc)4 / benzene / 20 °C 4.1: NaBH4 / methanol / 0 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 16, # 11 p. 1897 - 1900
反应条件
1: KIO4, H2SO4 / ethanol / 0.17 h / 40 °C 2: NaBH4 / ethanol / 2 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 47, # 36 p. 7625 - 7634
反应条件
1: alkaline hydrolysis 2: KIO4, H2SO4 / ethanol / 0.17 h / 40 °C 3: NaBH4 / ethanol / 2 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 47, # 36 p. 7625 - 7634
反应条件
poly((R)-2,2'-dihydroxy-5,5'-dicarboxy-1,1'-binaphthalene-copper complex) T=40°C; 24 h; Resolution of racemate; optical yield given as percent eeenantioselective reaction;
参考文献
New Journal of Chemistry, , vol. 34, # 11 p. 2389 - 2391
反应条件
poly((R)-2,2'-dihydroxy-5,5'-dicarboxy-1,1'-binaphthalene-copper complex) T=60°C; 24 h; Resolution of racemate; optical yield given as percent eeenantioselective reaction;
参考文献
New Journal of Chemistry, , vol. 34, # 11 p. 2389 - 2391
