2,3,4,5,6-五氟溴化苄合成路线 （共 48 条）
反应条件
pentacarbonyliron(0); tris-(dimethylamino)-phosphine in chlorobenzene
T=110°C; Zaitsev-Barbier reaction;
参考文献
Terent'Ev; Vasil'Eva; Ambartsumyan; Chakhovskaya; Mysova; Kochetkov
Russian Journal of Organic Chemistry, 2009 , vol. 45, # 8 p. 1181 - 1184
反应条件
diiron nonacarbonyl in hexane
参考文献
Birchall,J.M.; Haszeldine,R.N.
Journal of the Chemical Society, 1961 , p. 3719 - 3727
反应条件
magnesium; phosphorus trichoride
1.) Et2O, 2.) 0 deg C, 15 min; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Krafczyk, Roland; Thoennessen, Holger; Jones, Peter G.; Schmutzler, Reinhard
Journal of Fluorine Chemistry, 1997 , vol. 83, # 2 p. 159 - 166
反应条件
T=727 - 800°C; ΔE(excit.); KineticsThermodynamic dataProduct distribution;
参考文献
Kominar, R. John; Krech, Michael J.; Price, Stanley James W.
Canadian Journal of Chemistry, 1980 , vol. 58, p. 1906 - 1908
反应条件
in water; acetonitrile
T=20°C; 48 h; Overall yield = 40 percent; Overall yield = 367 mg;
参考文献
Giese, Michael; Albrecht, Markus; Steike, Simon; Ackermann, Anton; Valkonen, Arto; Rissanen, Kari
Inorganic Chemistry, 2013 , vol. 52, # 13 p. 7666 - 7672
反应条件
1: xylene
2: (i) nBuLi, benzene, (ii) /BRN= 1071571/
View Scheme
参考文献
Filler,R.; Choe,E.W.
Canadian Journal of Chemistry, 1975 , vol. 53, p. 1491 - 1495
反应条件
catalyst: Et4NBr in N,N-dimethyl-formamide
mixt. of pentafluorobenzyl bromide and Hg in satd. soln. of Et4NBr in dry DMF agitated (sealed ampoule, in the dark, Ar, 90 h);; ppt. filtered off, washed with ether, dried, (chromy. of the mother liquor: silica gel, CHCl3-hexane (2:1), protected from light);;
参考文献
Butin, K. B.; Ivkina, A. A.; Reutov, O. A.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1985 , vol. 34, p. 613 - 620
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1985 , vol. 34, p. 672 - 678
反应条件
1.1: 89 percent / propiononitrile / Heating
2.1: tBuLi / diethyl ether; hexane / 0.33 h / -78 °C
2.2: diethyl ether; hexane / 1 h / -78 - 20 °C
View Scheme
参考文献
Ishihara, Kazuaki; Hasegawa, Aiko; Yamamoto, Hisashi
Angewandte Chemie - International Edition, 2001 , vol. 40, # 21 p. 4077 - 4079
