1: 2-(2,6-dibromophenyl)-1,3-dioxane With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1.91667 h; 2: methyl iodide in tetrahydrofuran; hexane T=-78 - 20°C; 1.91667 h; 3: With hydrogenchloride; water in tetrahydrofuran; hexane T=20°C; 1.5 h;

1: 2-(2,6-dibromophenyl)-1,3-dioxane With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1.5 h; 2: methyl iodide in tetrahydrofuran; hexane T=-78 - 20°C; 1.91667 h; Further stages.;

1: pyridine / dichloromethane / 1 h / 20 °C 2: N-bromosuccinmide; Ag(1-)*C2F3O2(1-); palladium diacetate / 1,2-dichloro-ethane / 4 h / 120 °C 3: formaldehyd; toluene-4-sulfonic acid / tetrahydrofuran; water / 0.25 h / 100 °C / Microwave irradiation View Scheme

potassium carbonate; trifluoroacetic acid 1.) 120 deg C, 500 MPa, 9 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;